Medary.com

The science guys did a study:

"Although the purpose of both of these studies was to glean insights into metabolic physiology, our findings suggest that increased levels of FGF21 may be a potential mechanism behind low-carbohydrate diets' beneficial properties when it comes to lipid metabolism," says Maratos-Flier. "Diets that limit carbohydrates and eliminate transfats, and at the same time emphasize fiber and good fats, appear to be healthiest, especially among individuals who are predisposed to developing diabetes."

(Emphasis mine)